Optimistic Observer 09/11/25


By Capital Investment Counsel - September 11, 2025

CRISPR Moves From Breakthrough to Bedside: Life-Saving Therapy and Dozens More in the Pipeline
A custom CRISPR therapy has saved the life of a young boy with a fatal, ultra-rare genetic disorder—the first time a gene-editing treatment was developed specifically for a single patient. Created in under a year and delivered under emergency FDA approval, the therapy successfully reversed the disease, showing that CRISPR can now be deployed rapidly, safely, and with life-changing results.
At the same time, CRISPR is expanding far beyond one-off cases. A recent report highlights at least 40 CRISPR-based therapies currently in clinical trials, targeting everything from cancer to genetic blindness. Together, these breakthroughs mark a turning point: CRISPR is no longer just a lab tool but is now becoming a real medical option for patients with few alternatives. Read more here and here.

Voyager 1 Reconnects with Earth Thanks to Backup Thrusters
NASA engineers restored communication with Voyager 1 by activating its backup thrusters, solving a months-long issue. The fix extends the mission of the 47-year-old spacecraft, which continues to send data from beyond the solar system. Read more here.

Clean Water and Sanitation Reached 96.2 Million Africans Over the Past Decade
The African Development Bank reports that its initiatives have provided safe drinking water and sanitation to 96.2 million people across Africa since 2015. These improvements are part of broader efforts to raise living standards and promote public health. The results show steady, large-scale progress toward long-term development goals. Read more here

New Brain Implant Helps Paralyzed Patients Use Devices with Their Thoughts
A new brain implant from Synchron is helping people with severe paralysis control phones and computers just by thinking, without needing risky brain surgery. The device is inserted through blood vessels, making the procedure safer and less invasive. Read more here.

1.4 Billion People Now Living Healthier Lives, Says New WHO Report
The World Health Organization reports that 1.4 billion more people are living healthier lives thanks to gains in clean water, reduced tobacco use, and better air quality. Progress was also made in emergency preparedness and maternal and child health, with deaths under age 5 cut by more than half since 2000. Read more here.

MIT Researchers Use AI to Predict Protein Locations in Human Cells
MIT scientists have developed an AI model that can accurately predict where proteins are located inside human cells. This a key step in understanding how cells function. This breakthrough could speed up drug discovery and deepen insight into diseases at the molecular level. Read more here
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